The standard metaphors used to describe DNA and development are examined, including the claim that DNA "makes" protein, that DNA is "self-replicating" and the organisms "adapt" to their environments. In this lecture by distinguished evolutionary geneticist Richard Lewontin, he explains that DNA is manufactured by the cell machinery, that proteins are folded by rules that are not related to DNA sequence and that organisms, rather than adapting to their environment, are actively engaging in constructing their own environments, so that organisms and environments co-evolve...   more »

human/cow embryonic stem cells
Photo courtesy University of Wisconsin Board of Regents

Although some have concerns about the crossing of human and ape species, the possible creation of a hybrid Hanuman or other entities previously thought to belong only to myth :

"In April 2005, the National Academies -- chartered by Congress to advise the nation on matters of science -- released a report affirming that scientists should be allowed to create such entities if the experiments were approved by special review boards. The advisers came down against the creation of human-monkey or human-ape embryos, as well as experiments in which a human-like brain might develop in a non-human animal" wp.

The UK has just approved research for the crossing the boarders of human bovine species limits to harvest stem cells:

"The bill would allow scientists to continue injecting human DNA into cows' eggs that have had virtually all their genetic material removed, as well as other hybrid embryo processes for stem cell research. Scientists say the embryos would not be allowed to develop for more than 14 days. "wp

In England apparently there has been a long reasoned debate on the issue, one has to wonder however what is going on with embryo research in emerging nations where the market for experimentation may be seen in only the context of its exchange value. Whatever the case it appears our future bodies will in some way or other cohabit, or draw upon a physical (subtle physical) world shared with other species

What follows is a report from the Washington Post on recent events in England along with some further context of chimeras from the Center on Bioethics and Public Policy. rc...

Inter-species hybrids and chimera are entities created from the mixing of two or more different species. Hybrids are organisms whose genetic make up has been created by mixing the genes of two or more species; typically the gametes of two species are fused to create a single zygote. Chimera are organisms consisting of two or more different populations of genetically distinct cells; for example two fertilised eggs or early embryos may be fused together and develop as a single organism....
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(courtesy Google Images)

This paper seeks a long overdue critical exploration of Sri Aurobindo's evolutionary vision and how it might inform contemporary discourse on globalization and those regimes of techno-science whose productions propel its advance. That such a critical inquiry is overdue is regrettable because we live at a time in which we are undergoing what is perhaps our most rapid period of change in human history. We live in an era in which the dislocation of our physical, life and mental worlds seems to result from the pull of three strange attractors accelerating at different speeds.

Gazing out from the edge of digital culture in North America to do a critically inquiry into the future is problematic because our perspectives are already conjoined to the gaze of a culture entrained in exponential change. But what would constitute a future view? An epistemology of the Other? A discourse on the never quite? The future is that distant coordinate which is only know through its proximity to our present. So what does the present teach?

In America we are travelling so rapidly that from here we do not hear the voices of indentured knowledge workers standing in lines of up to mile, amidst the smoke and decay of south India, to compete with the multitudes of Heidegger's “standing reserve” for their conditions of economic bondages; of eight to twelve partitioned hours a day spent facilitating the global flow of virtual capital. Although the gaze from here may sense the desiring nature of the machine it lacks an epistemology for coping with its assemblages and a methodology for resisting its discipline.....

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In the six short chapters contained in Biology as Ideology, Richard Lewontin, a renowned geneticist, sets about clarifying the relationship between genes, society and genetics. In particular, he scrutinizes the dominance acquired by genetic determinism as a mechanism of causation.

Biology as Ideology once earned the title ‘most subversive book’ of 1993. How is it that this book, indeed any science book, could earn such a title? The chief reason is that Lewontin recognizes what few scientists do, that the respectability attained by biological, and particularly genetic, determinism is not simply an error of scientific judgment. It is instead an example of the tendency for interactions between scientists and those with power to be mutually accommodating. ...    - rc
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If complexity metaphors can be problematic when applied to social phenomena because they often reduce historic inequalities of socio-economic status to mere patterns of self-organization, metaphors of increasing complexity can be misused when combined with socially constructed ideas of progress. Stephen Jay Gould at least thought as much and this review of The Game of Life outlines some of the problems with equating increasing complexity with directional progress rc ...   more »

...a team of Japanese geneticists...announced that they had taught relativity to a bacterium, sort of.

Using the same code that computer keyboards use, the Japanese group, led by Masaru Tomita of Keio University, wrote four copies of Albert Einstein’s famous formula, E=mc2, along with “1905,” the date that the young Einstein derived it, into the bacterium’s genome, the 4.2-million-long string of A’s, G’s, T’s and C’s that determine everything the little bug is and everything it’s ever going to be.

The point was not to celebrate Einstein. The feat, they said in a paper published in the journal Biotechnology Progress, was a demonstration of DNA as the ultimate information storage material, able to withstand floods, terrorism, time and the changing fashions in technology, not to mention the ability to be imprinted with little unobtrusive trademark labels — little “Made by Monsanto” tags, say. ...   more »

University of Utah researchers have discovered a surprisingly tiny new messenger in worms: protons. The find raises the possibility that the subatomic particle plays the same role in humans, the researchers say. ...   more »

Here's another excerpt from Michael Talbot's fascinating book The Holographic Universe. I continue to recommend this book.

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...Other experiences included the accessing of racial and collective memories. Individuals of Slavic origin experienced what it was like to participate in the conquests of Genghis Khan's Mongolian hordes, to dance in trance with the Kalahari bushmen, to undergo the initiation rites of the Australian aborigines, and to die as sacrificial victims of the Aztecs. And again the descriptions frequently contained obscure historical facts and a degree of knowledge that was often completely at odds with the patient's education, race, and previous exposure to the subject. For instance, one uneducated patient gave a richly detailed account of the techniques involved in the Egyptian practice of embalming and mummification, including the form and meaning of various amulets and sepulchral boxes, a list of the materials used in the fixing of the mummy cloth, the size and shape of the mummy bandages, and other esoteric facets of Egyptian funeral services. Other individuals tuned into the cultures of the Far East and not only gave impressive descriptions of what it was like to have a Japanese, Chinese, or Tibetan psyche, but also related various Taoist or Buddhist teachings.

In fact, there did not seem to be any limit to what Grof's LSD subjects could tap into. They seemed capable of knowing what it was like to be every animal, and even plant, on the tree of evolution. They could experience what it was like to be a blood cell, an atom, a thermonuclear process inside the sun, the consciousness of the entire planet, and even the consciousness of the entire cosmos. More than that, they displayed the ability to transcend space and time, and occasionally they related uncannily accurate precognitive information. In an even stranger vein they sometimes encountered nonhuman intelligences during their cerebral travels, discarnate beings, spirit guides from "higher planes of consciousness," and other suprahuman entities...

Perhaps Grof's most remarkable discovery is that the same phenomena reported by individuals who have taken LSD can also be experienced without resorting to drugs of any kind...The Grofs call their technique holotropic therapy and use only rapid and controlled breathing, evocative music, and massage and body work, to induce altered states of consciousness. To date, thousands of individuals have attended their workshops and report experiences that are every bit as spectacular and emotionally profound as those described by subjects of Grof's previous work on LSD...   more »

You're taking a couple of prescription medications and you develop a cold -- so you head to the nearest pharmacy to get something for your headache, cough and stuffy nose.

Not so fast, experts advise. Mixing medications can be dangerous-- even deadly, a fact highlighted by the death in November of popular R&B singer Gerald Levert. An autopsy determined that Levert, 40 -- who reportedly had been suffering from a shoulder problem, pneumonia and the effects of surgery in 2005 to repair a severed Achilles tendon -- died of accidental acute intoxication caused by a mixture of the pain medications Darvocet, Percocet and Vicodin, the anxiety medicine Xanax and two over-the-counter antihistamines.

A report this month by the Centers for Disease Control and Prevention found that deaths from accidental drug interactions rose 68 percent between 1999 and 2004, continuing a steady climb since the early 1990s. Unintentional drug poisonings accounted for nearly 20,000 deaths in 2004, said the CDC, making the problem now the second-leading cause of accidental death in the United States, after automobile accidents. "Prescription drugs, especially prescription painkillers, are driving the prolonged increase," the report stated. ...   more »

"An ambitious project to create an accurate computer model of the brain has reached an impressive milestone," writes today's Technology Review. "Scientists in Switzerland working with IBM researchers have shown that their computer simulation of the neocortical column, arguably the most complex part of a mammal's brain, appears (emphasis added) to behave like its biological counterpart. By demonstrating that their simulation is realistic, the researchers say, these results suggest that an entire mammal brain could be completely modeled within three years, and a human brain within the next decade..."

The article goes onto to share the response of Christof Koch from Caltech who calls the 10 year target of modeling the human brain "ridiculous." Despite the fantastic progress to date I agree with Christof on this. ...   more »

Optimism exists on a continuum in between confidence and hope. Let me take these in order.

I am confident that the acceleration and expanding purview of information technology will solve within twenty years the problems that now preoccupy us. -- Consider energy. We are awash in energy (10,000 times more than required to meet all our needs falls on Earth) but we are not very good at capturing it. That will change with the full nanotechnology-based assembly of macro objects at the nano scale, controlled by massively parallel information processes, which will be feasible within twenty years. Even though our energy needs are projected to triple within that time, we'll capture that .0003 of the sunlight needed to meet our energy needs with no use of fossil fuels, using extremely inexpensive, highly efficient, lightweight, nano-engineered solar panels, and we'll store the energy in highly distributed (and therefore safe) nanotechnology-based fuel cells. Solar power is now providing 1 part in 1,000 of our needs, but that percentage is doubling every two years, which means multiplying by 1,000 in twenty years.

Almost all the discussions I've seen about energy and its consequences (such as global warming) fail to consider the ability of future nanotechnology-based solutions to solve this problem. This development will be motivated not just by concern for the environment but also by the $2 trillion we spend annually on energy. This is already a major area of venture funding.

Consider health. As of just recently, we have the tools to reprogram biology. This is also at an early stage but is progressing through the same exponential growth of information technology, which we see in every aspect of biological progress. The amount of genetic data we have sequenced has doubled every year, and the price per base pair has come down commensurately. The first genome cost a billion dollars. The National Institutes of Health is now starting a project to collect a million genomes at $1,000 apiece. We can turn genes off with RNA interference, add new genes (to adults) with new reliable forms of gene therapy, and turn on and off proteins and enzymes at critical stages of disease progression. We are gaining the means to model, simulate, and reprogram disease and aging processes as information processes. In ten years, these technologies will be 1,000 times more powerful than they are today, and it will be a very different world, in terms of our ability to turn off disease and aging. ...   more »

I can vouch for John Todd's research. I knew him back in the 70's and was impressed then with the quality of his work. His "Eco Machines" are the outcome of 30 years of research and trial and error experimentation. ~ ronjon

Social responsibility, sustainability, and 'natural capitalism' are becoming new models for governments and corporations in the 21st century...

The ECO Machine - a wastewater treatment system that naturally treats sewage and industrial waste to re-use quality. An important consideration as fresh water becomes one of the most important commodities in the new millennium...ECO Machines bring advanced wastewater treatment technology, and unsurpassed aesthetic, economic, and environmental advantages to companies, communities, and resorts both at home and internationally.

ECO Machines accelerate nature's own water purification process. Unlike chemical-based systems, ECO Machines incorporate helpful bacteria, fungi, plants, snails, clams, and fish that thrive by breaking down and digesting organic pollutants, pollutants that normally deprive the water of oxygen. This clean, simple approach efficiently transforms high-strength industrial wastewater and sewage into water clean enough to be recycled for reuse. ...   more »

...Researchers excavating a cave on the southern coast of South Africa discovered a bowl's worth of edible shellfish dating back to about 165,000 years ago, when Africa was colder and drier—pushing back the earliest known seafood meal by 40,000 years.

The team found small stone blades and reddish rocks tossed in with the shells; the rocks were marked in a way that suggests they were ground into powder used to make paint, possibly to adorn the face or body to symbolize status or membership in a group... -- "We've shown pretty strongly that people [were] working with pigments [164,000 years ago], which is a pretty good indicator of symbolic thought," Marean says. ...   more »

A new ultraviolet mosaic from NASA's Galaxy Evolution Explorer shows a speeding star that is leaving an enormous trail of "seeds" for new solar systems. The star, named Mira (pronounced my-rah) after the latin word for "wonderful," is shedding material that will be recycled into new stars, planets and possibly even life as it hurls through our galaxy.

Mira appears as a small white dot in the bulb-shaped structure at right, and is moving from left to right in this view. The shed material can be seen in light blue. The dots in the picture are stars and distant galaxies. The large blue dot at left is a star that is closer to us than Mira.

The Galaxy Evolution Explorer discovered Mira's strange comet-like tail during part of its routine survey of the entire sky at ultraviolet wavelengths. When astronomers first saw the picture, they were shocked because Mira has been studied for over 400 years yet nothing like this has ever been documented before. ...   more »

Bio-dynamised water, believed to cure various ailments including diabetes and heart problems, is set to hit Indian markets with a research centre at Auroville township near here commercially launching the equipment to produce it.

Aqua Dyn, the centre that has developed commercially viable equipment to carry out the "bio-dynamising" technique developed in France in the early 20th century, has been selling the processed water within the township for the past five years...

"Bio-dynamised water helps remove toxins from the body and has proven properties to heal diseases, including arthritis, diabetes, skin cancer and heart ailments," he said. ...   more »